Hydrazine hydrate (1:1) → HCID 21432164, compound

HRID 2398935Notes

Reaction equation

HRID 2398935 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([CH:14]=[CH:15][C:16]=1[NH:17][C:18](=[O:20])[CH3:19])[C:7]([CH2:9][CH2:10][C:11](O)=[O:12])=O)([O-:3])=[O:2].O.[NH2:22][NH2:23]>C(O)(=O)C>[N+:1]([C:4]1[CH:5]=[C:6]([C:7]2[CH2:9][CH2:10][C:11](=[O:12])[NH:22][N:23]=2)[CH:14]=[CH:15][C:16]=1[NH:17][C:18](=[O:20])[CH3:19])([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 21432172HCID 21432172, compound

Product 1

HCID 21432164HCID 21432164, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

32.5 gm of 3-(3'-nitro-4'-acetylamino-benzoyl)-propionic acid were added toa solution of 32.5 gm of hydrazine hydrate in 180 ml of glacial acetic acid, and the mixture was heated on a steam bath. After cooling, the precipitate formed thereby was suction-filtered off and washed with ether,yielding the desired compound; m.p. 223° C.

Workup

  1. temperaturethe mixture was heated on a steam bath
  2. temperatureAfter cooling
  3. customthe precipitate formed
  4. filtrationthereby was suction-filtered off
  5. washwashed with ether,yielding the desired compound

Sources & evidence

ORD record
ord-244fd778e2cb4baa9c27f04b9e53b9e4
Source dataset
uspto-grants-1977_05
Patent number
US04026891

Reaction notes

Loading…