4-Aminophenylacetic acid → HCID 70560746, compound

HRID 2399010Notes

Reaction equation

HRID 2399010 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]([OH:11])=[O:10])=[CH:4][CH:3]=1.[OH-].[CH2:13]([N+:17]([CH2:26][CH2:27][CH2:28][CH3:29])([CH2:22][CH2:23][CH2:24][CH3:25])[CH2:18][CH2:19][CH2:20][CH3:21])[CH2:14][CH2:15][CH3:16]>>[NH2:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:8][C:9]([O-:11])=[O:10])=[CH:6][CH:7]=1.[CH2:26]([N+:17]([CH2:13][CH2:14][CH2:15][CH3:16])([CH2:18][CH2:19][CH2:20][CH3:21])[CH2:22][CH2:23][CH2:24][CH3:25])[CH2:27][CH2:28][CH3:29]

Participants

3

Reactant 2

HCID 145334-Aminophenylacetic acidHCID 2723671Tetrabutylammonium Hydroxide

Product 1

HCID 70560746HCID 70560746, compound

Procedure

p-Aminophenylacetic acid (3.02 g) was dissolved in 51.9 g of 10% aqueous tetrabutylammonium hydroxide, and the solution was evaporated under reduced pressure to an amber oil. Upon further drying at 0.1 mm pressure at room temperature, a green solid was obtained. After rinsing with tetrahydrofuran there was obtained 4.696 g of nearly colorless crystals of tetrabutylammonium p-aminophenylacetate.

Workup

  1. customthe solution was evaporated under reduced pressure to an amber oil
  2. customUpon further drying at 0.1 mm pressure at room temperature
  3. customa green solid was obtained
  4. washAfter rinsing with tetrahydrofuran

Sources & evidence

ORD record
ord-69ff3facd2654ca18add40fca3ea291f
Source dataset
uspto-grants-1977_05
Patent number
US04026916

Reaction notes

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