HCID 9250987, compound → HCID 16080835, compound

HRID 2399278Notes

Reaction equation

HRID 2399278 reaction equation
[N+:1]([C:4]1[CH:20]=[CH:19][CH:18]=[CH:17][C:5]=1[O:6][C:7]1[CH:16]=[CH:15][CH:14]=[CH:13][C:8]=1[C:9]([O:11][CH3:12])=[O:10])([O-])=O>C(OCC)(=O)C.[Pd]>[NH2:1][C:4]1[CH:20]=[CH:19][CH:18]=[CH:17][C:5]=1[O:6][C:7]1[CH:16]=[CH:15][CH:14]=[CH:13][C:8]=1[C:9]([O:11][CH3:12])=[O:10]

Participants

4

Reactant 1

HCID 9250987HCID 9250987, compound

Product 1

HCID 16080835HCID 16080835, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

Methyl 2-(2-nitrophenoxy)benzoate (540 mg, 0.00198 mol) was dissolved in ethyl acetate (20 mL) and palladium on carbon catalyst (270 mg) was added. The mixture was hydrogenated at 57 psi for 2 h. The catalyst was filtered and the solvents were evaporated to yield the title compound. 1H NMR (250 MHz, CDCl3) δ7.83 (dd, 1H), 7.41 (m, 1H), 7.10 (m, 1H), 6.97 (m, 2H), 6.82 (m, 2H), 6.69 (m, 1H).

Workup

  1. filtrationThe catalyst was filtered
  2. customthe solvents were evaporated

Sources & evidence

ORD record
ord-3aaeb6604fbb4331ac8a03762779fca0
Source dataset
uspto-grants-1995_09
Patent number
US05447957

Reaction notes

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