1-Bromooctane → HCID 19384518, compound

HRID 2399784Notes

Reaction equation

HRID 2399784 reaction equation
[CH:1]1[C:9]2[C:8]3[CH2:10][CH2:11][CH2:12][CH2:13][C:7]=3[NH:6][C:5]=2[CH:4]=[C:3]([C:14]#[N:15])[CH:2]=1.Br[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24]>>[CH2:17]([CH:10]1[C:8]2[C:9]3[CH:1]=[CH:2][C:3]([C:14]#[N:15])=[CH:4][C:5]=3[NH:6][C:7]=2[CH2:13][CH2:12][CH2:11]1)[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24]

Participants

3

Reactant 2

HCID 81401-BromooctaneHCID 19384553HCID 19384553, compound

Product 1

HCID 19384518HCID 19384518, compoundYield 71.7%

Procedure

Using the procedure described in Example 9, 10.2 g of the carbonitrile from Example 2 was alkylated with 12.8 g of 1-bromooctane to give 11.5 g (68.5%) of 5,6,7,8-tetrahydro-9-octyl-9H-dibenzo[b,d]pyrrole-3-carbonitrile as a white solid.

Sources & evidence

ORD record
ord-9008c4e2a7bd489dadd83427dd9cb59c
Source dataset
uspto-grants-1995_09
Patent number
US05451600

Reaction notes

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