1-Bromooctane → HCID 19384458, compound

HRID 2399796Notes

Reaction equation

[CH3:1][C:2]1([CH3:23])[CH2:22][C:6]2=[N:7][C:8]3[C:9]([CH2:10][CH:11]=[CH:12][C:13]=3[O:14][CH2:15][C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[C:5]2[CH2:4][CH2:3]1.Br[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32]>>[CH3:1][C:2]1([CH3:23])[CH2:22][C:6]2=[N:7][C:8]3[C:9]([CH:10]([CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])[CH:11]=[CH:12][C:13]=3[O:14][CH2:15][C:16]3[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=3)=[C:5]2[CH2:4][CH2:3]1

Participants

Reactant 2

HCID 81401-Bromooctane

HCID 19384577HCID 19384577, compound

Product 1

HCID 19384458HCID 19384458, compoundYield 94%

Procedure

Using the procedure of Example 9, the alkylation of 4.3 g of 1,2,3,4-tetrahydro-3,3-dimethyl-6-phenylmethoxy-9H-dibenzo[b,d]pyrrole from Example 59 was reacted with 2.92 g of 1-bromooctane to produce 5.5 g (94%) of 1,2,3,4-tetrahydro-3,3-dimethyl-6-phenylmethoxy -9-octyl-9H-dibenzo[b,d]pyrrole as a white solid after chromatographic purification.

Sources & evidence

ORD record: ord-389626751a1748888180aa99da79f4b8
Source dataset: uspto-grants-1995_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05451600

Reaction notes

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