1-Bromooctane → HCID 19384471, compound

HRID 2399799Notes

Reaction equation

[CH2:1]([CH:9]1[C:17]2[C:13](=[N:14][C:15]3[C:16]=2[CH2:18][CH:19]=[CH:20][C:21]=3[O:22][CH2:23][C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[CH2:12][CH2:11][CH2:10]1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].Br[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38]>>[CH2:1]([CH:9]1[C:17]2[C:13](=[N:14][C:15]3[C:16]=2[CH:18]([CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38])[CH:19]=[CH:20][C:21]=3[O:22][CH2:23][C:24]2[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=2)[CH2:12][CH2:11][CH2:10]1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

Reactant 2

HCID 81401-Bromooctane

HCID 19384493HCID 19384493, compound

Product 1

HCID 19384471HCID 19384471, compoundYield 61.7%

Procedure

Using the procedure of Example 9, 2.9 g of 1,2,3,4-tetrahydro-1-octyl-6-phenylmethoxy-9H-dibenzo[b,d]pyrrole from Example 62 was alkylated with 1.68 g of 1-bromooctane to produce 2.3 g (61.7%) of rac-1,2,3,4-tetrahydro-1,9-dioctyl-6-phenylmethoxy-9H-dibenzo[b,d]pyrrole as a yellow oil after chromatographic purification.

Sources & evidence

ORD record: ord-5943a61b091f4364bd8f63f89c5ca3b7
Source dataset: uspto-grants-1995_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05451600

Reaction notes

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