反应详情

温度

60 °C

1,30-Triacontadiol (38) (2.5 g, 5.5 mmol) was dissolved in dry, ethanol free chloroform at 60° C. under nitrogen and treated with pyridine (0.49 ml; 6.05 mmol). The resulting solution was treated with a solution of linoleoyl chloride (39) (1.64 g; 5.5 mmol) in chloroform (20 ml) over a twenty minute period and then maintained at 60° C. for a further thirty minutes, then cooled, diluted with chloroform, washed with water three times, dried, filtered and evaporated. The crude product obtained in this manner was purified on silica (30 g). Elution with chloroform gives the title compound (40) as a white solid (1.73 g; 44%).

1. customin dry
2. temperaturecooled
3. washwashed with water three times
4. customdried
5. filtrationfiltered
6. customevaporated
7. customThe crude product obtained in this manner
8. customwas purified on silica (30 g)
9. washElution with chloroform