Chloride → HCID 22292062, compound

HRID 2400116Notes

Reaction equation

[NH2:1][CH:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3]1.[C:11](=O)([O-])[O-].[K+].[K+].[Cl-:17].[C:18](#N)[CH3:19]>>[ClH:17].[CH2:11]([NH:1][CH:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3]1)[C:18]#[CH:19]

Participants

Reactant 4

HCID 312Chloride

HCID 6342Acetonitrile

HCID 11430Potassium Carbonate

HCID 123445(+-)-1-Aminoindan

Product 1

HCID 22292062HCID 22292062, compound

Conditions

Temperature: 60 °C

Procedure

Racemic 1-aminoindan (10.0 g) and 10.4 g of potassium carbonate were added to 75 ml of acetonitrile. The resulting suspension was heated to 60° C. and 4.5 g of proparyl chloride were added dropwise.

Sources & evidence

ORD record: ord-4bc3a0d9deec4bd19d5834deebb8f644
Source dataset: uspto-grants-1995_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05453446

Reaction notes

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