反应详情

DIEA (49.9 μL, 0.29 mmol) was added to 7-Methoxy-benzofuran-2-carboxylic acid (50 mg, 0.26 mmol) and HATU (108.8 mg, 0.29 mmol) in 1 mL of DMF with constant stirring at room temperature until a clear solution resulted. Subsequently, 3-Imidazo[1,2-a]pyridin-2-yl-phenylamine (54.4 mg, 0.26 mmol) was added and allowed to react overnight when a solid precipitated out of solution. The resulting precipitate was filtered, dried under suction, and finally dried overnight in vacuo to give the final product: LCMS (ESI) m/z 384 (MH+).

1. customresulted
2. customto react overnight when a solid
3. customprecipitated out of solution
4. filtrationThe resulting precipitate was filtered
5. customdried under suction, and finally dried overnight in vacuo