反应详情

A round-bottom flask was charged with 3-[(4-nitro-1H-indol-1-yl)methyl]-1-(t-butyloxycarbonyl)-1H-pyrrolo[2,3-b]pyridine (510 mg, 1.3 mmol), Pd/C (50 mg, 10%) and THF (30 mL). The mixture was then stirred under a hydrogen atmosphere for 2 h, filtered, and concentrated under reduced pressure to afford 3-[(4-amino-1H-indol-1-yl)methyl]-1-(t-butyloxycarbonyl)-1H-pyrrolo[2,3-b]pyridine (470 mg).

1. filtrationfiltered
2. concentrationconcentrated under reduced pressure