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HRID2406629

反应详情

EQUATION

反应方程式

HRID 2406629 的结构方程式

REACTANTS

反应物

4
结构：O=C1CCCC(=O)O1
HCID7940

Glutaric anhydride

C5H6O3

结构：[K+].[OH-]
HCID14797

Potassium hydroxide

HKO

结构：[Cl-].[NH4+]
HCID25517

未命名化合物

结构：CCCCCCc1cc2ccccc2[nH]1
HCID14299246

未命名化合物

PRODUCTS

生成物

1
结构：CCCCCCc1cc2ccccc2n1C(=O)CCCC(=O)O
HCID49804576

2-Hexyl-δ-oxo-1H-indole-1-pentanoic acid

C19H25NO3

AUXILIARIES

试剂、催化剂与溶剂

2
结构：CS(C)=O
溶剂HCID679

Dimethyl sulfoxide

C2H6OS

结构：CCOC(C)=O
溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

To a solution of 2-hexyl-1H-indole in DMSO was added KOH at RT and was stirred for 30 minutes. Then to this mixture dihydro-pyran-2,6-dione was added and stirred for 3 hours. The reaction was treated with saturated ammonium chloride and ethyl acetate. The product was purified by column chromatography.

WORKUP

后处理

  1. stirringstirred for 3 hours
  2. customThe product was purified by column chromatography