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HRID2406672

反应详情

EQUATION

反应方程式

HRID 2406672 的结构方程式

REACTANTS

反应物

3
结构：O
HCID962

Water

H2O

结构：CCOC(C)=O
HCID8857

Ethyl acetate

C4H8O2

结构：CCCCCCc1cc2ccc(Cl)cc2n1C(=O)C[C@@H](C)CC(=O)OC
HCID66644021

未命名化合物

PRODUCTS

生成物

1
结构：CCCCCCc1cc2ccc(Cl)cc2n1C(=O)C[C@@H](C)CC(=O)O
HCID49802315

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

To the solution of 5-(6-Chloro-2-hexyl-indol-1-yl)-3-(R)-methyl-5-oxo-pentanoic acid methyl ester in THF was added 1.2N HCL and was stirred at 60 0 C for 30 hours. The reaction mixture was then treated with water and ethyl acetate. The product was purified by column chromatography.

WORKUP

后处理

  1. customThe product was purified by column chromatography