反应详情

To the cold suspension of hexyl-triphenyl-phosphonium bromide in THF was added LiHMDS in THF and the mixture was stirred for 30 minutes and then the solution of 5-chloro-1H-indole-2-carbaldehyde was added to the reaction mixture and stirred for 3 hours. The reaction was quenched with saturated ammonium chloride solution and extracted with ethyl acetate. The product, 5-chloro-2-hept-1-enyl-1H-indole was purified by column chromatography.

1. stirringstirred for 3 hours
2. customThe reaction was quenched with saturated ammonium chloride solution
3. extractionextracted with ethyl acetate
4. customThe product, 5-chloro-2-hept-1-enyl-1H-indole was purified by column chromatography