Hydrogen Bromide → Hydrogen Bromide

HRID 2407220Notes

Reaction equation

HRID 2407220 reaction equation
C[O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH:9]1[CH2:14][CH2:13][CH2:12][NH:11][CH2:10]1.Cl.[BrH:16]>>[BrH:16].[NH:11]1[CH2:12][CH2:13][CH2:14][CH:9]([C:4]2[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=2[OH:2])[CH2:10]1

Participants

5

Reactant 3

HCID 260Hydrogen BromideHCID 313Hydrochloric AcidHCID 129379303-(2-Methoxyphenyl)piperidine

Product 2

HCID 260Hydrogen BromideHCID 205026332-(Piperidin-3-yl)phenol

Procedure

HBr was prepared by heating 3-(2-methoxyphenyl)piperidine.HCl (46 mg, 0.20 mmol) with 48% HBr in a microwave reactor at 120° C. for one hour. After evaporation, 61 mg of the title compound was obtained.

Workup

  1. customAfter evaporation

Sources & evidence

ORD record
ord-a6d93d1dbd8c4534baea82c3619c9ffa
Source dataset
uspto-grants-2014_08
Patent number
US08809536B2

Reaction notes

Loading…