Hydrogen Bromide → Hydrogen Bromide

HRID 2407221Notes

Reaction equation

HRID 2407221 reaction equation
C[O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[CH2:14][CH2:13][CH2:12][NH:11][CH2:10]2)=[CH:5][CH:4]=1.Cl.[BrH:16]>>[BrH:16].[NH:11]1[CH2:12][CH2:13][CH2:14][CH:9]([C:6]2[CH:5]=[CH:4][C:3]([OH:2])=[CH:8][CH:7]=2)[CH2:10]1

Participants

5

Reactant 3

HCID 260Hydrogen BromideHCID 313Hydrochloric AcidHCID 129379203-(4-Methoxyphenyl)piperidine

Product 2

HCID 260Hydrogen BromideHCID 22326681HCID 22326681, compound

Procedure

HBr was prepared by heating 3-(4-methoxyphenyl)piperidine.HCl (46 mg, 0.20 mmol) with 48% HBr in a microwave reactor at 120° C. for one hour. After evaporation, 53 mg of the title compound was obtained.

Workup

  1. customAfter evaporation

Sources & evidence

ORD record
ord-4813b14adbd541a189ade3d2cf59d758
Source dataset
uspto-grants-2014_08
Patent number
US08809536B2

Reaction notes

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