Hydrochloric Acid → HCID 58504035, compound

HRID 2407654Notes

Reaction equation

HRID 2407654 reaction equation
O.[OH-].[Li+].[NH2:4][C:5]1[C:10]([Cl:11])=[C:9]([O:12][CH2:13][CH3:14])[N:8]=[C:7]([C:15]([O:17]C)=[O:16])[C:6]=1[Cl:19].O.Cl>C(O)C>[NH2:4][C:5]1[C:10]([Cl:11])=[C:9]([O:12][CH2:13][CH3:14])[N:8]=[C:7]([C:15]([OH:17])=[O:16])[C:6]=1[Cl:19]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 962WaterHCID 168937Lithium hydroxide, monohydrateHCID 58504256HCID 58504256, compound

Product 1

HCID 58504035HCID 58504035, compoundYield 67.5%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Lithium hydroxide monohydrate (0.027 g) was added to a room temperature solution of the compound prepared in Example 2 (0.172 g) in ethanol (0.5 mL)-water (0.3 mL). The mixture was stirred for two hours and then brought to pH 3 via the addition of 1 N hydrochloric acid. The precipitated solids were collected by filtration to obtain the title compound (0.110 g) having the following physical data.

Workup

  1. filtrationThe precipitated solids were collected by filtration

Sources & evidence

ORD record
ord-45c28be93c7b4828830750136d9a328d
Source dataset
uspto-grants-2014_08
Patent number
US08809538B2

Reaction notes

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