Hydrochloric Acid → HCID 66989693, compound

HRID 2407745Notes

Reaction equation

HRID 2407745 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1[S:11][C:10]([S:12]([N:15]2[CH2:20][CH2:19][CH:18]([CH2:21][NH:22]C(=O)OC(C)(C)C)[CH2:17][CH2:16]2)(=[O:14])=[O:13])=[CH:9][CH:8]=1.[ClH:30]>ClCCl.O1CCOCC1>[ClH:30].[ClH:30].[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1[S:11][C:10]([S:12]([N:15]2[CH2:16][CH2:17][CH:18]([CH2:21][NH2:22])[CH2:19][CH2:20]2)(=[O:13])=[O:14])=[CH:9][CH:8]=1

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 86659059HCID 86659059, compound

Product 1

HCID 66989693HCID 66989693, compound

Reagents, catalysts & solvents 2

HCID 6344DichloromethaneSolventHCID 312751,4-DioxaneSolvent

Procedure

A solution of the compound prepared in Example 243 (0.088 g) in dichloromethane (1 mL) was treated with 4N hydrogen chloride in dioxane (0.151 mL) at room temperature. The mixture was stirred at room temperature for 18 hours. The solvent was evaporated in vacuo to provide the title compound (0.072 g) having the following physical data.

Workup

  1. customThe solvent was evaporated in vacuo

Sources & evidence

ORD record
ord-28b8c455a42e41f98b01939d3dce6c80
Source dataset
uspto-grants-2014_08
Patent number
US08809538B2

Reaction notes

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