反应详情

2.5 g of 2,2-dimethylpropane-1,3-diamine and 2.17 g of guanidine hydrochloride are heated to 140° C. under argon for 4 h. After returning to RT, add ethanol and dry evaporate. 3.9 g (yield=95%) of 5,5-dimethyl-1,4,5,6-tetrahydropyrimidin-2-amine hydrochloride are obtained as a white powder used as such.

1. customAfter returning to RT
2. customdry
3. customevaporate