Hydrochloric Acid → HCID 67381459, compound

HRID 2409441Notes

Reaction equation

HRID 2409441 reaction equation
[CH3:1][N:2]([CH3:23])[CH:3]([C:5]1[CH:6]=[CH:7][C:8]2[C:17]3[NH:16][CH2:15][CH2:14][CH2:13][C:12]=3[C:11](=[O:18])[N:10](COC)[C:9]=2[CH:22]=1)[CH3:4].[ClH:24]>C(O)C>[ClH:24].[ClH:24].[CH3:23][N:2]([CH3:1])[CH:3]([C:5]1[CH:6]=[CH:7][C:8]2[C:17]3[NH:16][CH2:15][CH2:14][CH2:13][C:12]=3[C:11](=[O:18])[NH:10][C:9]=2[CH:22]=1)[CH3:4]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 58424894HCID 58424894, compound

Product 1

HCID 67381459HCID 67381459, compoundYield 86%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
80 °C

Procedure

The compound (15 mg, 0.05 mmol) prepared in step 6 was dissolved in ethanol (4 ml) and added with conc. hydrochloric acid (0.5 ml). The mixture was stirred overnight at 80° C. and the precipitate was collected by filteration to obtain the title compound (14 mg, yield: 86%, yellow solid).

Workup

  1. customthe precipitate was collected by filteration

Sources & evidence

ORD record
ord-c5484744c64f4c8ea8d131bcb40da1ee
Source dataset
uspto-grants-2014_08
Patent number
US08815891B2

Reaction notes

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