Fluoroacetic acid → HCID 66821535, compound

HRID 241032Notes

Reaction equation

[Br:1][C:2]1[CH:3]=[C:4]([NH2:9])[C:5]([NH2:8])=[CH:6][CH:7]=1.[F:10][CH2:11][C:12](O)=O.Cl[C:16]([O:18][CH2:19][CH:20]([CH3:22])[CH3:21])=[O:17]>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]2[N:8]([C:16]([O:18][CH2:19][CH:20]([CH3:22])[CH3:21])=[O:17])[C:12]([CH2:11][F:10])=[N:9][C:4]=2[CH:3]=1

Participants

Reactant 3

HCID 5237Fluoroacetic acid

HCID 62365Isobutyl chloroformate

HCID 3235934-Bromobenzene-1,2-diamine

Product 1

HCID 66821535HCID 66821535, compound

Procedure

Synthesized according to the method of reagent preparation 19 using 4-bromobenzene-1,2-diamine and fluoroacetic acid in step 1 then treatment with isobutyl chloroformate in step 3. MS (EI) for C13H14BrFN2O2: 330 (MH+).

Workup

customSynthesized

Sources & evidence

ORD record: ord-dcf8639aceb34a2cb462eec33a2473f6
Source dataset: uspto-grants-2014_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08648066B2

Reaction notes

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