m-Chloroperbenzoic acid → 4-(3-Ethanesulphonylpropyl)-2-fluoro-1-triphenylmethylimidazole

HRID 2412501Notes

Reaction equation

HRID 2412501 reaction equation
[CH2:1]([S:3]([CH2:5][CH2:6][CH2:7][C:8]1[N:9]=[C:10]([F:32])[N:11]([C:13]([C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:12]=1)=[O:4])[CH3:2].ClC1C=CC=C(C(OO)=[O:41])C=1>>[CH2:1]([S:3]([CH2:5][CH2:6][CH2:7][C:8]1[N:9]=[C:10]([F:32])[N:11]([C:13]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)([C:26]2[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=2)[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:12]=1)(=[O:41])=[O:4])[CH3:2]

Participants

3

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 204324204-(3-Ethanesulphinylpropyl)-2-fluoro-1-triphenylmethylimidazole

Product 1

HCID 204323174-(3-Ethanesulphonylpropyl)-2-fluoro-1-triphenylmethylimidazole

Procedure

Using the same technique as for the starting material of Example 50, but using two equivalents of 3-chloroperbenzoic acid, there was obtained 4-(3-ethanesulphonylpropyl)-2-fluoro-1-triphenylmethylimidazole, having the following n.m.r. in CDCl3 : 1.35 (t, 3H); 2.09 (quintet, 2H); 2.58 (t, 2H); 2.84 (q, 4H); 6.29 (s, 1H); 7.0-7.4 (m, 15H).

Sources & evidence

ORD record
ord-0de220272dce44cab58481c99229c3d0
Source dataset
uspto-grants-1985_01
Patent number
US04492692

Reaction notes

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