Ethanol → Ethyl bis(pentafluoroethyl)phosphinite

HRID 241310Notes

Reaction equation

HRID 241310 reaction equation
[F:1][C:2]([P:8](Cl)[C:9]([F:15])([F:14])[C:10]([F:13])([F:12])[F:11])([F:7])[C:3]([F:6])([F:5])[F:4].[CH2:17]([OH:19])[CH3:18]>CN(C)C1C=CN=CC=1.C(OCC)C>[F:1][C:2]([P:8]([C:9]([F:15])([F:14])[C:10]([F:13])([F:12])[F:11])[O:19][CH2:17][CH3:18])([F:7])[C:3]([F:6])([F:5])[F:4]

Participants

5

Reactant 2

HCID 702EthanolHCID 2757428Bis(pentafluoroethyl)phosphinous chloride2×

Product 1

HCID 86653812Ethyl bis(pentafluoroethyl)phosphinite

Reagents, catalysts & solvents 2

HCID 142844-(Dimethylamino)pyridineCatalystHCID 3283Diethyl EtherSolvent

Procedure

Bis(pentafluoroethyl)phosphinous acid chloride, (C2F5)2PCl, obtainable in accordance with Example 2, is added to a mixture of ethanol and 4-dimethylaminopyridine in diethyl ether at room temperature. The precipitated product 4-dimethylaminopyridinium chloride is separated off, and the solution comprises ethyl bis(pentafluoroethyl)phosphinite, (C2F5)2POC2H5.

Workup

  1. customThe precipitated product 4-dimethylaminopyridinium chloride is separated off

Sources & evidence

ORD record
ord-eda27c680cc84ed38fcae7051d4ad4c6
Source dataset
uspto-grants-2014_02
Patent number
US08648202B2

Reaction notes

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