反应详情

5.8 g of the compound prepared under (b) are heated under reflux for 16 hours with a mixture of 100 ml of glacial acetic acid and 48% strength aqueous hydrobromic acid in the volume ratio 1:1. After cooling, the acid mixture is distilled off under waterpump vacuum, and the residue is boiled with a little ethanol. On cooling and scratching, 4.0 g of colorless crystals crystallize out (47% of theory over all stages), melting point: 165-166°.

1. temperatureare heated
2. temperatureAfter cooling
3. distillationthe acid mixture is distilled off under waterpump vacuum
4. temperatureOn cooling
5. custom4.0 g of colorless crystals crystallize out (47% of theory over all stages), melting point: 165-166°