Oxalyl chloride → 2-Chlorobenzoyl isocyanate

HRID 2414357Notes

Reaction equation

HRID 2414357 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH2:6])=[O:5].C(Cl)(=O)[C:12](Cl)=[O:13]>ClCCl>[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([N:6]=[C:12]=[O:13])=[O:5]

Participants

4

Reactant 2

HCID 65578Oxalyl chlorideHCID 691112-Chlorobenzamide

Product 1

HCID 99423112-Chlorobenzoyl isocyanate

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

2-Chlorobenzamide was dissolved in dichloromethane, mixed with 1.5 eq. of oxalyl chloride and heated to reflux for 16 hours. The reaction mixture was concentrated under high vacuum and reacted in stage b without further purification.

Workup

  1. temperatureheated
  2. temperatureto reflux for 16 hours
  3. concentrationThe reaction mixture was concentrated under high vacuum
  4. customreacted in stage b without further purification

Sources & evidence

ORD record
ord-60e4d6686d774ac7a0ecdf1fe5091626
Source dataset
uspto-grants-2004_11
Patent number
US06812250B2

Reaction notes

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