Heptane → HCID 10224239, compound

HRID 2415239Notes

Reaction equation

HRID 2415239 reaction equation
[CH3:1][C:2]1[C:3]([Se:16][C:17]#[C:18][C:19]2[CH:28]=[CH:27][C:22]([C:23]([O:25]C)=[O:24])=[CH:21][CH:20]=2)=[CH:4][C:5]2[C:6]([CH3:15])([CH3:14])[CH2:7][CH2:8][C:9]([CH3:13])([CH3:12])[C:10]=2[CH:11]=1.CCCCCCC>C1COCC1.[OH-].[Na+]>[CH3:1][C:2]1[C:3]([Se:16][C:17]#[C:18][C:19]2[CH:20]=[CH:21][C:22]([C:23]([OH:25])=[O:24])=[CH:27][CH:28]=2)=[CH:4][C:5]2[C:6]([CH3:15])([CH3:14])[CH2:7][CH2:8][C:9]([CH3:12])([CH3:13])[C:10]=2[CH:11]=1

Participants

5

Reactant 2

HCID 8900HeptaneHCID 22641081HCID 22641081, compound

Product 1

HCID 10224239HCID 10224239, compoundYield 80.4%

Reagents, catalysts & solvents 2

HCID 8028TetrahydrofuranSolventHCID 14798Sodium HydroxideSolvent

Procedure

In a manner similar to that of Example 7, by reaction of 1.35 g (3.07 mmol) of methyl 4-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-napthylselanylethynyl)benzoate in 20 ml of THF and 3 g of sodium hydroxide, and after trituration from heptane, 1.05 g (80%) of the expected compound are obtained in the form of a white solid. m.p.=240° C.

Sources & evidence

ORD record
ord-8b20f9729af14381a065b2060118494d
Source dataset
uspto-grants-2004_11
Patent number
US06818666B2

Reaction notes

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