反应详情

A saturated solution of hydrogen chloride in ethyl acetate (6 mL) was added to a solution of tert-butyl 4-[4-chloro-2-(2-methoxy-1-methyl-2-oxoethyl)phenyl]-3,6-dihydropyridine-1(2H)-carboxylate (0.730 g, 1.92 mmol) in methylene chloride (6 mL) at 0° C. After 1 h, the volatiles were evaporated in vacuo, and the crude residue triturated twice with dry diethyl ether to give 2-3 (0.605 g) (m/z (ES) 280 (MH+).

1. customthe volatiles were evaporated in vacuo
2. customthe crude residue triturated twice with dry diethyl ether