反应详情

A mixture of 2,7-diacetyloxy-9-methylfluorene (12 g), lithium hydroxide monohydrate (3.42 g) and ethylene glycol (120 mL) was refluxed for one hour by heating. The reaction mixture was poured into 6M-hydrochloric acid and extracted with ethyl acetate. The organic layer was sufficiently washed with water and then dried on anhydrous magnesium sulfate. The solvent was distilled off from this organic layer under reduced pressure to obtain 2,7-dihydroxy-9-methylfluorene (7.24 g) of light brown crystal. Melting point: 191.5-196.3° C.

1. temperaturewas refluxed for one hour
2. temperatureby heating
3. extractionextracted with ethyl acetate
4. washThe organic layer was sufficiently washed with water
5. dry with materialdried on anhydrous magnesium sulfate
6. distillationThe solvent was distilled off from this organic layer under reduced pressure