Dimethylformamide → HCID 15661106, compound

HRID 2417337Notes

Reaction equation

HRID 2417337 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([SH:8])[CH:5]=[CH:6][CH:7]=1.C(=O)([O-])[O-].[K+].[K+].CN(C=O)C.[Br-].[CH3:21][C:22]([CH3:25])=[CH:23][CH3:24]>O>[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([S:8][CH2:24][CH:23]=[C:22]([CH3:25])[CH3:21])[CH:3]=1

Participants

6

Reactant 4

HCID 6228DimethylformamideHCID 79303-ThiocresolHCID 11430Potassium CarbonateHCID 22634671HCID 22634671, compound

Product 1

HCID 15661106HCID 15661106, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

5 g (40 mmol) of 3-methylthiophenol, 5.6 g (40 mmol) of potassium carbonate and 50 ml of DMF are introduced into a three-necked flask. 7.2 g (48 mmol) of 3-methyl-2-butene bromide are added and the mixture is stirred at room temperature for four hours. The reaction medium is poured into water and extracted with ethyl ether, and the organic phase is separated out after settling has taken place, dried over magnesium sulphate and evaporated. 7.8 g (100%) of the expected product are collected in the form of a yellow oil.

Workup

  1. extractionextracted with ethyl ether
  2. customthe organic phase is separated out after settling
  3. dry with materialdried over magnesium sulphate
  4. customevaporated
  5. custom7.8 g (100%) of the expected product are collected in the form of a yellow oil

Sources & evidence

ORD record
ord-ab1062953d03440fb22dc80466f557ab
Source dataset
uspto-grants-2004_11
Patent number
US06825360B1

Reaction notes

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