Triethylamine → HCID 86589877, compound

HRID 2417500Notes

Reaction equation

HRID 2417500 reaction equation
[F:1][C:2]1[CH:3]=[CH:4][C:5]([N+:16]([O-:18])=[O:17])=[C:6]([CH:15]=1)[CH2:7][NH:8][CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11].[Cl:19][C:20]1[CH:28]=[CH:27][C:23]([C:24](Cl)=[O:25])=[CH:22][CH:21]=1.C(N(CC)CC)C>ClCCl>[F:1][C:2]1[CH:3]=[CH:4][C:5]([N+:16]([O-:18])=[O:17])=[C:6]([CH:15]=1)[CH2:7][N:8]([CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11])[C:24](=[O:25])[C:23]1[CH:27]=[CH:28][C:20]([Cl:19])=[CH:21][CH:22]=1

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 85014-Chlorobenzoyl chlorideHCID 21285525HCID 21285525, compound

Product 1

HCID 86589877HCID 86589877, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

1.15 g (3.95 mmol) of ethyl (5-fluoro-2-nitrobenzyl)aminoacetate was dissolved in 20 ml of dichloromethane. 0.61 ml (4.7 mmol) of 4-chlorobenzoyl chloride and 0.82 ml (5.9 mmol) of triethylamine were added to the obtained solution, and they were stirred at room temperature for 2 hours. After the treatment with dichloromethane as the extracting solvent by an ordinary method, the crude product was obtained.

Sources & evidence

ORD record
ord-06013a9daf2f4e70b632b8c151654a1f
Source dataset
uspto-grants-2004_11
Patent number
US06825191B2

Reaction notes

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