Benzoyl isocyanate, 2-methyl- → HCID 13041497, compound

HRID 2418311Notes

Reaction equation

HRID 2418311 reaction equation
[Cl:1][C:2]1([Cl:13])[CH2:4][CH:3]1[O:5][C:6]1[CH:12]=[CH:11][C:9]([NH2:10])=[CH:8][CH:7]=1.[CH3:14][C:15]1[CH:25]=[CH:24][CH:23]=[CH:22][C:16]=1[C:17]([N:19]=[C:20]=[O:21])=[O:18]>O1CCCC1>[Cl:1][C:2]1([Cl:13])[CH2:4][CH:3]1[O:5][C:6]1[CH:12]=[CH:11][C:9]([NH:10][C:20]([NH:19][C:17](=[O:18])[C:16]2[CH:22]=[CH:23][CH:24]=[CH:25][C:15]=2[CH3:14])=[O:21])=[CH:8][CH:7]=1

Participants

4

Reactant 2

HCID 12259962Benzoyl isocyanate, 2-methyl-HCID 13041496HCID 13041496, compound

Product 1

HCID 13041497HCID 13041497, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

6.54 g (0.03 Mol) of 4-(2,2-dichlorcyclopropyloxy)-aniline, dissolved in 50 ml dry tetrahydrofuran, are added dropwise with 4.84 g (0.03 Mol) of 2-methylbenzoyl-isocyanate, with stirring. The temperature increases mildly therewith. After cooling, the product is precipitated with pentane, withdrawn by suction, after-washed with pentane and dried.

Workup

  1. temperatureThe temperature increases mildly
  2. temperatureAfter cooling
  3. customthe product is precipitated with pentane
  4. customwithdrawn by suction
  5. washafter-washed with pentane
  6. customdried

Sources & evidence

ORD record
ord-9f743dcb08734b869fc4bd3da213e0b5
Source dataset
uspto-grants-1984_09
Patent number
US04472434

Reaction notes

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