反应详情

To a stirred mixture of 74.2 g (0.455 moles) ##STR16## ethylphosphonothioic dichloride in 400 ml benzene, 30.1 g (0.5 moles) isopropyl alcohol was added. To that mixture 50.6 g (0.5 moles) triethylamine was added at a dropwise rate overnight. The mixture was then warmed for about 1 hour. The mixture was filtered by gravity. Most of the solvent (benzene) was stripped off under reduced pressure and heat to give ethyl-O-isopropylphosphonothioic chloride: ##STR17##

1. additionwas added
2. temperatureThe mixture was then warmed for about 1 hour
3. filtrationThe mixture was filtered by gravity
4. temperatureheat