(5-Ethyl-1-azabicyclo(2.2.2)octan-2-yl)(6-methoxyquinolin-4-yl)methanol → HCID 178436996, compound

HRID 2418872Notes

Reaction equation

HRID 2418872 reaction equation
CCC1CN2CCC1CC2C(O)c1ccnc2ccc(OC)cc12.O=S(O)C(F)F.[Zn]>CC(C)(C)OO.ClCCl.O.O=C(O)C(F)(F)F>CCC1CN2CCC1CC2C(O)c1cc(C(F)F)nc2cc(C(F)(F)F)c(OC)cc12

Participants

7

Reactant 2

HCID 3649(5-Ethyl-1-azabicyclo(2.2.2)octan-2-yl)(6-methoxyquinolin-4-yl)methanolHCID 89600919HCID 89600919, compound

Product 1

HCID 178436996HCID 178436996, compoundYield 49%

Reagents, catalysts & solvents 4

HCID 6410tert-Butyl hydroperoxideReagentHCID 6422Trifluoroacetic acidReagentHCID 962WaterSolventHCID 6344DichloromethaneSolvent

Conditions

Temperature
25 °C

Sources & evidence

ORD record
ord-228a58906ec043d9a9d51f0a53134781
Source dataset
Minisci dataset from Roche

Reaction notes

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