2-Methylquinoxaline → 2-(Fluoromethyl)-3-methylquinoxaline

HRID 2418892Notes

Reaction equation

HRID 2418892 reaction equation
Cc1cnc2ccccc2n1.O=S(O)CF.[Zn]>CC(C)(C)OO.ClCCCl.O>Cc1nc2ccccc2nc1CF

Participants

6

Reactant 2

HCID 236862-MethylquinoxalineHCID 178527420HCID 178527420, compound

Product 1

HCID 1190859342-(Fluoromethyl)-3-methylquinoxalineYield 56%

Reagents, catalysts & solvents 3

HCID 6410tert-Butyl hydroperoxideReagentHCID 111,2-DichloroethaneSolventHCID 962WaterSolvent

Conditions

Temperature
50 °C

Sources & evidence

ORD record
ord-db31077e5f7c4fffabce623357f9686f
Source dataset
Minisci dataset from Roche

Reaction notes

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