(5-Ethyl-1-azabicyclo(2.2.2)octan-2-yl)(6-methoxyquinolin-4-yl)methanol → HCID 178436995, compound

HRID 2418908Notes

Reaction equation

HRID 2418908 reaction equation
CCC1CN2CCC1CC2C(O)c1ccnc2ccc(OC)cc12.O=S(O)C(F)(F)F.[Zn]>CC(C)(C)OO.ClCCCl.O>CCC1CN2CCC1CC2C(O)c1cc(C(C)C)nc2cc(C(F)(F)F)c(OC)cc12.O=C(O)C(F)(F)F

Participants

6

Reactant 2

HCID 3649(5-Ethyl-1-azabicyclo(2.2.2)octan-2-yl)(6-methoxyquinolin-4-yl)methanolHCID 89601280CID 89601280

Product 1

HCID 178436995HCID 178436995, compoundYield 30%

Reagents, catalysts & solvents 3

HCID 6410tert-Butyl hydroperoxideReagentHCID 111,2-DichloroethaneSolventHCID 962WaterSolvent

Conditions

Temperature
25 °C

Sources & evidence

ORD record
ord-8235176dec414924a108950bb935cb59
Source dataset
Minisci dataset from Roche

Reaction notes

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