Hydrochloric Acid → HCID 20316441, compound

HRID 2418982Notes

Reaction equation

HRID 2418982 reaction equation
[CH:1]1[C:11]2[CH2:10][CH2:9][C:8]3[CH:12]=[CH:13][CH:14]=[CH:15][C:7]=3[S:6][C:5]=2[CH:4]=[CH:3][C:2]=1[CH2:16][C:17]([OH:19])=[O:18].Cl>C(O)CC(C)C>[CH:1]1[C:11]2[CH2:10][CH2:9][C:8]3[CH:12]=[CH:13][CH:14]=[CH:15][C:7]=3[S:6][C:5]=2[CH:4]=[CH:3][C:2]=1[CH2:16][C:17]([O:19][CH2:11][CH2:1][CH:2]([CH3:16])[CH3:3])=[O:18]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 12443712HCID 12443712, compound

Product 1

HCID 20316441HCID 20316441, compound

Reagents, catalysts & solvents 1

HCID 31260Isoamyl AlcoholSolvent

Procedure

A solution of 250 mg. of 10,11-dihydrodibenzo[b.f]thiepin-2-acetic acid in 30 ml. of isoamyl alcohol is saturated with hydrogen chloride. After 90 minutes, the excess alcohol is distilled off under reduced pressure to yield isoamyl 10,11-dihydrodibenzo[b.f]thiepin-2-acetate, which can be further purified by thin layer chromatography.

Workup

  1. distillationthe excess alcohol is distilled off under reduced pressure

Sources & evidence

ORD record
ord-f07707b1f3824f7f8b85f00c0f5fed94
Source dataset
uspto-grants-1978_08
Patent number
US04104280

Reaction notes

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