Hydrochloric Acid → HCID 12737000, compound

HRID 2419024Notes

Reaction equation

HRID 2419024 reaction equation
[CH2:1](Cl)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:9]1([CH:15]2[CH2:20][NH:19][CH2:18][C:17]3[S:21][CH:22]=[CH:23][C:16]2=3)[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.Cl>C(O)(C)C>[CH2:1]([N:19]1[CH2:20][CH:15]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[C:16]2[CH:23]=[CH:22][S:21][C:17]=2[CH2:18]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 7503Benzyl ChlorideHCID 127369914-Phenyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine

Product 1

HCID 12737000HCID 12737000, compoundYield 52%

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

Benzyl chloride is condensed with 4-phenyl-4,5,6,7-tetrahydro-thieno[2,3-c]pyridine (Example 3), according to the procedure of Example 8. Hydrochloride; M.p. = 185° C (isopropanol); Yield: 52%.

Sources & evidence

ORD record
ord-775be643a6c94210840afe6ea7a5dc1a
Source dataset
uspto-grants-1978_08
Patent number
US04104390

Reaction notes

Loading…