Iodoethane → HCID 86735929, compound

HRID 2419784Notes

Reaction equation

HRID 2419784 reaction equation
[CH2:1]([NH:3][C:4](=[S:7])[NH:5][NH2:6])[CH3:2].[CH2:8]([I:10])C>C(O)C>[IH:10].[CH2:1]([N:3]=[C:4]([S:7][CH3:8])[NH:5][NH2:6])[CH3:2]

Participants

4

Reactant 2

HCID 6340IodoethaneHCID 15517804-Ethyl-3-thiosemicarbazide

Product 1

HCID 86735929HCID 86735929, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A stirred solution of 97.0 g. of 4-ethyl-3-thiosemicarbazide and 127.8 g. of ethyl iodide in 500 ml. of ethanol is heated under reflux for 18 hours. The reaction mixture is concentrated under reduced pressure, diluted with n-hexane and filtered, giving the desired product as a nearly colorless solid, m.p. 73°-74° C.

Workup

  1. temperatureunder reflux for 18 hours
  2. concentrationThe reaction mixture is concentrated under reduced pressure
  3. additiondiluted with n-hexane
  4. filtrationfiltered

Sources & evidence

ORD record
ord-e0776027656244c8bee7a5346ac006f6
Source dataset
uspto-grants-1978_08
Patent number
US04107326

Reaction notes

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