Benzyl Chloride → 1-Benzyl-3,4-diethylpyridin-1-ium chloride

HRID 2420027Notes

Reaction equation

HRID 2420027 reaction equation
[CH2:1]([Cl:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:9]([C:11]1[CH:12]=[N:13][CH:14]=[CH:15][C:16]=1[CH2:17][CH3:18])[CH3:10]>C(O)(C)C>[Cl-:8].[CH2:1]([N+:13]1[CH:14]=[CH:15][C:16]([CH2:17][CH3:18])=[C:11]([CH2:9][CH3:10])[CH:12]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 7503Benzyl ChlorideHCID 691513,4-Diethylpyridine

Product 1

HCID 203381101-Benzyl-3,4-diethylpyridin-1-ium chloride

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

Benzyl chloride (250 g.) was added dropwise to a stirred and refluxed solution of 3,4-diethylpyridine (262 g.) and isopropyl alcohol (700 ml.). Repeated concentration under vacuum and addition of benzene afforded a slurry of crystalline 1-benzyl-3,4-diethyl-pyridinium chloride.

Workup

  1. concentrationconcentration
  2. additionunder vacuum and addition of benzene

Sources & evidence

ORD record
ord-84e712d38cec4785bd027dd88436149f
Source dataset
uspto-grants-1978_08
Patent number
US04108857

Reaction notes

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