HCID 20313223, compound → HCID 20313231, compound

HRID 2420160Notes

Reaction equation

HRID 2420160 reaction equation
[H-].[Al+3].[Li+].[H-].[H-].[H-].[CH2:7]([N:11]1[C:16](=O)[CH2:15][O:14][CH:13]([CH2:18][O:19][C:20]2[CH:21]=[CH:22][CH:23]=[C:24]3[C:28]=2[CH2:27][CH:26]=[CH:25]3)[CH2:12]1)[CH2:8][CH2:9][CH3:10]>O1CCCC1>[CH2:7]([N:11]1[CH2:16][CH2:15][O:14][CH:13]([CH2:18][O:19][C:20]2[CH:21]=[CH:22][CH:23]=[C:24]3[C:28]=2[CH2:27][CH:26]=[CH:25]3)[CH2:12]1)[CH2:8][CH2:9][CH3:10]

Participants

4

Reactant 2

HCID 20313223HCID 20313223, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 20313231HCID 20313231, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent2×

Procedure

In 250 ml. of anhydrous tetrahydrofuran was suspended 2.0 g. of lithium aluminum hydride and then a solution prepared by dissolving 8.0 g. of 4-butyl-2-(7-indenyloxymethyl)morpholin-5-one in 50 ml. of anhydrous tetrahydrofuran was added slowly to the suspension with stirring. Then, by treating the mixture in a similar manner as in Example 1, 6.4 g. (yield) of oily 4-butyl-2-(7-indenyloxymethyl)-morpholine was obtained.

Workup

  1. dissolutionby dissolving 8.0 g
  2. additionThen, by treating the mixture in a similar manner as in Example 1, 6.4 g

Sources & evidence

ORD record
ord-a067caeea1674e1798d17031c2f92526
Source dataset
uspto-grants-1978_08
Patent number
US04109088

Reaction notes

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