HCID 20313213, compound → HCID 20313218, compound

HRID 2420161Notes

Reaction equation

HRID 2420161 reaction equation
[H-].[Al+3].[Li+].[H-].[H-].[H-].[CH2:7]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][C:14]=2[O:16][CH2:17][CH:18]2[O:23][CH2:22][C:21](=O)[N:20]([CH3:25])[CH2:19]2)[CH:9]=[CH:8]1>O1CCCC1>[CH2:7]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][C:14]=2[O:16][CH2:17][CH:18]2[O:23][CH2:22][CH2:21][N:20]([CH3:25])[CH2:19]2)[CH:9]=[CH:8]1

Participants

4

Reactant 2

HCID 20313213HCID 20313213, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 20313218HCID 20313218, compoundYield 38%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent2×

Procedure

In 200 ml. of anhydrous tetrahydrofuran was suspended 1.4 g. of lithium aluminum hydride and after adding thereto slowly a solution prepared by dissolving 5.8 g. of 2-(7-indenyloxymethyl)-4-methylmorpholin-5-one in 30 ml. of tetrahydrofuran, the mixture was treated in a similar manner as in Example 1 to provide 2.1 g. (yield 38%) of oily 2-(7-indenyloxymethyl)-4-methylmorpholine.

Workup

  1. customslowly a solution prepared
  2. dissolutionby dissolving 5.8 g
  3. customto provide 2.1 g

Sources & evidence

ORD record
ord-a509a62614434aa58730184fd5dc1959
Source dataset
uspto-grants-1978_08
Patent number
US04109088

Reaction notes

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