4-Hydroxybenzaldehyde → HCID 67243971, compound
Reaction equation
[NH2:1][C:2]1[N:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[CH2:11]([NH2:14])[CH:12]=[CH2:13].[OH:15][C:16]1[CH:23]=[CH:22][C:19]([CH:20]=O)=[CH:18][CH:17]=1.[Br-].Br[CH2:26][CH2:27][CH2:28][NH+:29]1[CH2:33][CH2:32][CH2:31][CH2:30]1>>[CH2:11]([N:14]1[C:4](=[O:6])[C:3]2[CH:7]=[CH:8][CH:9]=[N:10][C:2]=2[N:1]=[C:20]1[C:19]1[CH:22]=[CH:23][C:16]([O:15][CH2:26][CH2:27][CH2:28][N:29]2[CH2:33][CH2:32][CH2:31][CH2:30]2)=[CH:17][CH:18]=1)[CH:12]=[CH2:13]Participants
5
Procedure
The entitled compound was obtained according to the method of Example 77 but using 2-aminonicotinic acid, allylamine, 4-hydroxybenzaldehyde and 1-(3-bromopropyl)pyrrolidinium bromide.
Workup
- customThe entitled compound was obtained
Sources & evidence
- ORD record
- ord-331c3fc7880f47f3829e0f2e47dae3fb
- Source dataset
- uspto-grants-2011_06
- Patent number
- US07960394B2
Reaction notes
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