Trifluoroacetic acid → HCID 67242360, compound

HRID 2423056Notes

Reaction equation

C(OC([NH:8][CH2:9][C:10](O)=[O:11])=O)(C)(C)C.[NH2:13][CH2:14][CH:15]1[CH2:17][CH2:16]1.[C:18]([OH:24])([C:20]([F:23])([F:22])[F:21])=[O:19]>>[F:21][C:20]([F:23])([F:22])[C:18]([OH:24])=[O:19].[NH2:8][CH2:9][C:10]([NH:13][CH2:14][CH:15]1[CH2:17][CH2:16]1)=[O:11]

Participants

Reactant 3

HCID 6422Trifluoroacetic acid

HCID 75646Cyclopropanemethanamine

HCID 78288N-(tert-butoxycarbonyl)glycine

Product 1

HCID 67242360HCID 67242360, compound

Procedure

The title was compound prepared from tert-Butoxycarbonylamino-acetic acid, using aminomethylcyclopropane and TFA, following procedures analogous to that described in Example 1A.

Sources & evidence

ORD record: ord-5fa5fe36c80048a8aa7c84fc695081a5
Source dataset: uspto-grants-2011_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07960560B2

Reaction notes

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