Hydroxylamine → HCID 178513298, compound

HRID 2423234Notes

Reaction equation

HRID 2423234 reaction equation
[NH2:1][OH:2].[C:3]([C:5]1[CH:6]=[C:7]([CH:11]=[CH:12][CH:13]=1)[C:8]([OH:10])=[O:9])#[N:4]>CO>[OH:2][NH:1][C:3](=[NH:4])[C:5]1[CH:6]=[C:7]([CH:11]=[CH:12][CH:13]=1)[C:8]([OH:10])=[O:9]

Participants

4

Reactant 2

HCID 787HydroxylamineHCID 158753-Cyanobenzoic acid

Product 1

HCID 178513298HCID 178513298, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

An aqueous 50% hydroxylamine solution was added to a methanol solution of 3-cyanobenzoic acid, followed by heating under reflux for 11 hours. The reaction liquid was concentrated, diluted with water, adjusted with 1 M hydrochloric acid to have a pH of from 2 to 3, and the precipitate was collected by filtration to obtain 3-[(hydroxyamino)(imino)methyl]benzoic acid. ES+: 181.

Workup

  1. temperatureby heating
  2. temperatureunder reflux for 11 hours
  3. customThe reaction liquid
  4. concentrationwas concentrated
  5. additiondiluted with water
  6. filtrationthe precipitate was collected by filtration

Sources & evidence

ORD record
ord-3981e0f0009a4b3eb4f2c690e29dce2a
Source dataset
uspto-grants-2011_06
Patent number
US07960562B2

Reaction notes

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