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HRID2423341

反应详情

EQUATION

反应方程式

HRID 2423341 的结构方程式

REACTANTS

反应物

1
结构：Cc1cc(CNC(=O)OC(C)(C)C)cc(Cl)c1NS(C)(=O)=O
HCID67242868

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc(CN)cc(Cl)c1NS(C)(=O)=O
HCID67242390

未命名化合物

收率 145.8%

AUXILIARIES

试剂、催化剂与溶剂

2
结构：O=C(O)C(F)(F)F
催化剂HCID6422

未命名化合物

结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

(3-Chloro-4-methanesulfonylamino-5-methyl-benzyl)-carbamic acid t-butyl ester (153.8 mg, 0.44 mmol) and CF3COOH (5˜6 drops) were added into methylene chloride. The mixture was stirred for 12 hrs. A reaction solvent was concentrated in vacuo to yield syrup (159.6 mg, 100%).

WORKUP

后处理

  1. concentrationA reaction solvent was concentrated in vacuo