反应详情

温度

60 °C

A solution of methyl 1-(1-methylethyl)-1H-pyrazole-3-carboxylate (0.13 g) in DMF (3 ml) was treated with N-chlorosuccinimide (0.103 g) and heated to 60° C. for 5 h under nitrogen. The cooled mixture was partitioned between diethyl ether (20 ml) and water (20 ml), separated, the organic extracts dried over sodium sulphate and evaporated to give the title compound as a pale yellow oil (0.105 g).

1. customThe cooled mixture was partitioned between diethyl ether (20 ml) and water (20 ml)
2. customseparated
3. dry with materialthe organic extracts dried over sodium sulphate
4. customevaporated