Hydrochloric Acid → HCID 19619889, compound

HRID 244619Notes

Reaction equation

HRID 244619 reaction equation
[Cl:1][C:2]1[C:3]([C:10]([O:12]C)=[O:11])=[N:4][N:5]([CH:7]([CH3:9])[CH3:8])[CH:6]=1.Cl>O1CCOCC1>[Cl:1][C:2]1[C:3]([C:10]([OH:12])=[O:11])=[N:4][N:5]([CH:7]([CH3:8])[CH3:9])[CH:6]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 50896795HCID 50896795, compound

Product 1

HCID 19619889HCID 19619889, compoundYield 100.3%

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Conditions

Temperature
105 °C

Procedure

To a solution of methyl 4-chloro-1-(1-methylethyl)-1H-pyrazole-3-carboxylate (105 mg) in 1,4-dioxane (3 ml) was added 2M hydrochloric acid (3 ml) and the mixture heated at 105° C. for 18 h. The solvent was removed in vacuo to give the title compound as a yellow oil (98 mg).

Workup

  1. customThe solvent was removed in vacuo

Sources & evidence

ORD record
ord-b216717d8a9f44fca9425a1d82a67ef7
Source dataset
uspto-grants-2014_02
Patent number
US08658635B2

Reaction notes

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