Hydrochloric Acid → HCID 21464694, compound

HRID 246896Notes

Reaction equation

HRID 246896 reaction equation
[CH3:1][OH:2].N1C=CC=CC=1.[CH3:9][C:10]1([C:18](Cl)=[O:19])[CH:15]([CH3:16])[CH2:14][C:13]([CH3:17])=[CH:12][CH2:11]1.Cl>O.C1(C)C=CC=CC=1>[CH3:1][O:2][C:18]([C:10]1([CH3:9])[CH:15]([CH3:16])[CH2:14][C:13]([CH3:17])=[CH:12][CH2:11]1)=[O:19]

Participants

7

Reactant 4

HCID 313Hydrochloric AcidHCID 887MethanolHCID 1049PyridineHCID 450816111,4,6-Trimethylcyclohex-3-ene-1-carbonyl chloride

Product 1

HCID 21464694HCID 21464694, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 1140TolueneSolvent

Procedure

0.2 moles (8 ml) methanol, 0.15 moles (12 ml) pyridine and 50 ml toluene were put in a 100-ml beaker with a magnetic stirrer, and the crude product as per (b) was (1,4,6-trimethylcyclohex-3-en-1-carboxylic acid chloride) added dosewise with vigorous stirring. The reaction mixture was stirred for another hour at room temperature and then 25 ml water and 5 ml concentrated hydrochloric acid were added to it. Then the phases were separated, the organic phase dried with sodium sulfate and distilled via the Vigreux column after removal of the solvent.

Workup

  1. additionadded dosewise with vigorous stirring
  2. customThen the phases were separated
  3. dry with materialthe organic phase dried with sodium sulfate
  4. distillationdistilled via the Vigreux column
  5. customafter removal of the solvent

Sources & evidence

ORD record
ord-a5b7b016d20349e0b32f16d50ed2cd19
Source dataset
uspto-grants-1987_11
Patent number
US04704477

Reaction notes

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