HCID 20163254, compound → HCID 20163251, compound

HRID 246909Notes

Reaction equation

HRID 246909 reaction equation
[CH2:1]([C:4]1[C:5]([OH:25])=[CH:6][C:7]2[O:11][CH:10]=[C:9]([C:12]3[CH:17]=[C:16]([O:18][CH3:19])[C:15]([O:20][CH3:21])=[C:14]([O:22][CH3:23])[CH:13]=3)[C:8]=2[CH:24]=1)[CH:2]=[CH2:3]>C(OCC)(=O)C.[Pd]>[OH:25][C:5]1[C:4]([CH2:1][CH2:2][CH3:3])=[CH:24][C:8]2[C:9]([C:12]3[CH:17]=[C:16]([O:18][CH3:19])[C:15]([O:20][CH3:21])=[C:14]([O:22][CH3:23])[CH:13]=3)=[CH:10][O:11][C:7]=2[CH:6]=1

Participants

4

Reactant 1

HCID 20163254HCID 20163254, compound

Product 1

HCID 20163251HCID 20163251, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

A solution of 5-allyl-6-hydroxy-3-(3,4,5-trimethoxyphenyl)benzofuran (300 mg) in ethyl acetate (2 ml) containing 5% palladium-on-charcoal was hydrogenated for 20 minutes. The mixture was filtered and the filtrate was evaporated to give 6-Hydroxy-3-(3,4,5-trimethoxyphenyl)-5-propylbenzofuran.

Workup

  1. filtrationThe mixture was filtered
  2. customthe filtrate was evaporated

Sources & evidence

ORD record
ord-774b639125db4b0fb99156e247eaba80
Source dataset
uspto-grants-1987_11
Patent number
US04704462

Reaction notes

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