Bromochloromethane → HCID 11658340, compound

HRID 247057Notes

Reaction equation

HRID 247057 reaction equation
C(N(CC)CC)C.[SH:8][C:9]1[N:10]([CH3:14])[CH:11]=[CH:12][N:13]=1.Br[CH2:16][Cl:17]>>[Cl:17][CH2:16][S:8][C:9]1[N:10]([CH3:14])[CH:11]=[CH:12][N:13]=1

Participants

4

Reactant 3

HCID 6333BromochloromethaneHCID 8471TriethylamineHCID 178480602HCID 178480602, compound

Product 1

HCID 11658340HCID 11658340, compound

Procedure

Triethylamine (40 mmol) was added to a mixture of 2-mercapto-1-methylimidazole (40 mmol) and bromochloromethane (0.8 mol). The mixture was stirred for 1 hour at room temperature, washed with water and the dried (MgSO4) solution evaporated. Yield: 5.85 g (90%). 1H NMR (CDCl3, δ): 3.77 (CH3), 5.00 (CH2), 6.7-7.2 (H-4 and H-5). The product was used in the succeeding step without further purification.

Workup

  1. washwashed with water
  2. dry with materialthe dried (MgSO4) solution
  3. customevaporated
  4. customThe product was used in the succeeding step without further purification

Sources & evidence

ORD record
ord-442e9d63f89444d7925b9119b14a6874
Source dataset
uspto-grants-1987_11
Patent number
US04705791

Reaction notes

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