Ammonium Hydroxide → HCID 20160706, compound

HRID 247441Notes

Reaction equation

HRID 247441 reaction equation
[C:1]([N:4]1[CH2:10][CH:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:8]2[CH:17]=[C:18]([O:25][CH3:26])[C:19]([S:21](Cl)(=[O:23])=[O:22])=[CH:20][C:7]=2[CH2:6][CH2:5]1)(=[O:3])[CH3:2].[OH-].[NH4+:28]>C(Cl)Cl>[C:1]([N:4]1[CH2:10][CH:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:8]2[CH:17]=[C:18]([O:25][CH3:26])[C:19]([S:21](=[O:23])(=[O:22])[NH2:28])=[CH:20][C:7]=2[CH2:6][CH2:5]1)(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 14923Ammonium HydroxideHCID 20160682HCID 20160682, compound

Product 1

HCID 20160706HCID 20160706, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

3-Acetyl-7-chlorosulfonyl-8-methoxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine (3.9 g, 0.01 m) is dissolved in methylene chloride (50 ml) and added to concentrated ammonium hydroxide (15 ml), then stirred and filtered to give 3-acetyl-8-methoxy-1-phenyl-7-sulfamoyl-2,3,4,5-tetrahydro-1H-3-benzazepine.

Workup

  1. filtrationfiltered

Sources & evidence

ORD record
ord-f1a16549fb684b3bbc207623c6133877
Source dataset
uspto-grants-1987_11
Patent number
US04707483

Reaction notes

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